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Unknown long-term effects : Because human studies are extremely limited, we simply do not know whether prolonged use carries risks
These include allergic reactions, which can be very serious
CNS Drugs 11 , 435448 (1999)
Most people are good candidates, but especially those who are vegetarian or vegan, take medications that deplete B12, have gut or absorption issues, or are dealing with chronic fatigue and brain fog
Also, certain medications, like proton pump inhibitors and metformin, might affect B12 absorption
A calculator cannot tell you whether retatrutide is appropriate for your situation
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